What does physics from Newton to the present day have to say about the nature of time and space? Is space a thing or just the lack of things between things? Does it have a preferred direction? Does time flow and what gives time its arrow? How did relativity and quantum theory affect the picture? What would be the implications of string theory and brane universes? Cosmology predicts a Big Bang and a heat death to the universe - is time therefore necessarily finite? The last talk allows time for an extended discussion on all matters time and space The subject will be discussed without advanced mathematics. A recommended companion course is Roy Moyser's on the Metaphysics of Time and Space (PHL 04) which will run monthly throughout this academic year.